The director confirmed during an appearance on Josh Horowitz‘s Happy Sad Confused podcast that a follow-up to the 2011 film is in the works.
“I’ve got a project in development that Scott Burns is working with me on, that’s a kind of philosophical sequel to Contagion but in a different context. You’ll kind of look at the two of them as kind of paired but very different hair colors. So, Scott and I had been talking about, ‘So, what’s the next iteration of a Contagion-type story?’ We have been working on that. We should probably hotfoot it a little bit,” he explained.